Cartridge information
Our cartridges are developed for research-use environments and engineered to support consistent, repeatable delivery with low residual volume. The design combines precision-formed internal geometry with a long-stopper system that travels further into the neck of the cartridge, helping to evacuate fluid efficiently.
They are a low dead space, high-recovery system — supporting efficient fluid delivery and minimal retained volume.
On this page
1. Cartridge design and performance
Typical residual volume is approximately 0.03–0.05 mL in a 3 mL cartridge, supporting consistent delivery across batches.
As with all cartridge and syringe systems, a small amount of residual volume is expected. Our cartridges are designed to operate within accepted performance ranges, delivering consistent results in real-world use under recognized injection system standards — including ISO 7886 and ISO 11608 — which govern dose accuracy and repeatable delivery.
Important: The residual volume is intentional. Never use 3D printed spacers or aftermarket modifications to try to extract it. Read why →
2. Cartridge models
We offer two 3 mL long-stopper cartridge models.
Classic
The traditional cartridge format. Requires venting during fill to prevent stopper blowout. See the Loading and Venting Guide for recommended fill techniques.
Pre-Purged Easy Load
Designed to simplify filling by eliminating the need for venting and reducing the risk of stopper blowouts. Self-sealing top, no vent required. See the Loading and Venting Guide for full instructions.
3. Sterilization process
How are the 3 mL cartridges sterilized?
For both cartridge models, individual components are steam sterilized prior to assembly. Components are then mechanically assembled in a controlled sterile environment, sealed in Tyvek steam sterilization pouches, and undergo a final steam sterilization cycle. Each pouch includes a visual steam indicator confirming proper exposure to sterilization conditions.
What type of packaging is used?
Cartridges are sealed in Tyvek steam sterilization pouches. Tyvek is widely used for steam sterilization because of its durability, breathability, and ability to maintain package integrity following autoclave processing.
Pen-Depot.com sells:
- Individually wrapped cartridges
- Multi-cartridge pouches (4–10 cartridges sealed in the same steam-sterilized pouch)
How can I tell the product has been steam sterilized?
Each sealed pouch includes a steam-activated visual indicator. The indicator changes color from blue to shades of black or green (depending on the pouch used) when the appropriate temperature and steam exposure conditions have been met during the autoclave cycle. This provides clear visual confirmation of processing.
4. Sterilization documentation
Do you provide sterilization certificates, validation logs, or testing reports?
No. We do not provide individual sterilization certificates, batch records, biological indicator results, or testing reports due to the volume of items sold.
Verification is provided solely by the visual steam indicator on the sealed pouch.
Our products are not marketed or classified as regulated medical devices. The sterilization process described reflects quality-controlled handling appropriate for the product's intended classification and use.
Why don't you offer additional sterilization documentation?
Individual certification and validation reporting is typically reserved for regulated medical or surgical devices. For our research product category, visual indicator verification on sealed sterilization pouches is the accepted standard.
5. Is this product right for you?
Customers are encouraged to assess suitability based on their own research requirements and intended use prior to purchase.
If additional documentation or regulatory validation is required for a specific research use case, this product may not be the appropriate fit.
Questions? Email info@pen-depot.com — we're happy to help you decide.
Questions? info@pen-depot.com · +1-267-737-8433